Based on data from 19 vehicles, 803 fuel-ups and 260,282 miles of driving, the 2007 Mercedes-Benz E350 gets a combined Avg MPG of 20.46 with a 0.36 MPG margin of error.

Any Engine Type 3.5L V6 GAS (16) V6 GAS (3) Any Body Style Sedan (6) Wagon (2) Any Submodel Elegance (2) Base (3) Sport (3) 4Matic (8) Other (3)

Below you can see a distribution of the fuel-ups with 31 outliers (3.72%) removed.

Following shows the average MPG of each of the 19 vehicles in the system.

• My E350

  2007 Mercedes-Benz E350 4Matic 3.5L V6 GAS Automatic 5 Speed
  Added Mar 2024 • 22 Fuel-ups

  Property of graphkoh

• 18.5 Avg MPG

• E350 Wagon

  2007 Mercedes-Benz E350 Elegance 3.5L V6 GAS Automatic 7 Speed Wagon
  Added Sep 2016 • 165 Fuel-ups

  Property of ajthanud

• 16.8 Avg MPG

• Mary Jane

  2007 Mercedes-Benz E350 3.5L V6 GAS Automatic 7 Speed
  Added Aug 2024 • 27 Fuel-ups

  Property of emtkopan

• 21.8 Avg MPG

• My E350 4MATIC

  2007 Mercedes-Benz E350 4Matic 3.5L V6 GAS Automatic 5 Speed
  Added Sep 2020 • 41 Fuel-ups

  Property of Hoback

• 21.5 Avg MPG

• E CLASS

  2007 Mercedes-Benz E350 Elegance 3.5L V6 GAS Automatic 7 Speed Sedan
  Added Jan 2018 • 103 Fuel-ups

  Property of davehfv

• 25.3 Avg MPG

• My E350 Wagon

  2007 Mercedes-Benz E350 4Matic 3.5L V6 GAS Automatic 5 Speed
  Added Jun 2021 • 31 Fuel-ups

  Property of Sumpfotter

• 21.9 Avg MPG

• Mercedes E350

  2007 Mercedes-Benz E350 4Matic 3.5L V6 GAS Automatic 5 Speed Sedan
  Added Oct 2020 • 8 Fuel-ups

  Property of iBanshee

• 15.1 Avg MPG

• My E350

  2007 Mercedes-Benz E350 Sport 3.5L V6 GAS Automatic 7 Speed
  Added Feb 2018 • 89 Fuel-ups

  Property of regmo77

• 22.1 Avg MPG

• Mercedes E350

  2007 Mercedes-Benz E350 3.5L V6 GAS Automatic 7 Speed Sedan
  Added Jul 2018 • 9 Fuel-ups

  Property of TNoote

• 24.2 Avg MPG

• My E350

  2007 Mercedes-Benz E350 4Matic 3.5L V6 GAS Automatic 5 Speed
  Added Feb 2018 • 3 Fuel-ups

  Property of Brad01mc

• 20.4 Avg MPG

• Emma

  2007 Mercedes-Benz E350 4Matic 3.5L V6 GAS Automatic 5 Speed Wagon
  Added Jan 2018 • 10 Fuel-ups

  Property of 85-Diesel

• 19.7 Avg MPG

• MB E350

  2007 Mercedes-Benz E350 3.5L V6 GAS Automatic 7 Speed Sedan
  Added May 2017 • 85 Fuel-ups

  Property of salestrada

• 22.9 Avg MPG

• 2007 Mercedes E-350

  2007 Mercedes-Benz E350 Sport 3.5L V6 GAS Automatic 7 Speed
  Added Mar 2017 • 46 Fuel-ups

  Property of willbeacher

• 25.5 Avg MPG

• Benz

  2007 Mercedes-Benz E350 Sport 3.5L V6 GAS Automatic 7 Speed Sedan
  Added Oct 2017 • 101 Fuel-ups

  Property of yorlik

• 27.4 Avg MPG

• xBenz

  2007 Mercedes-Benz E350 4Matic 3.5L V6 GAS Automatic 5 Speed Sedan
  Added Apr 2018 • 24 Fuel-ups

  Property of Pauline

• 21.1 Avg MPG

• Merc

  2007 Mercedes-Benz E350 4Matic 3.5L V6 GAS Automatic 5 Speed
  Added Mar 2017 • 30 Fuel-ups

  Property of rheilenman

• 17.6 Avg MPG

• e350

  2007 Mercedes-Benz E350 GAS V6
  Added Jul 2013 • 44 Fuel-ups

  Property of anewbie

• 20.6 Avg MPG

• Mike's Car

  2007 Mercedes-Benz E350 GAS V6
  Added Dec 2010 • 58 Fuel-ups

  Property of mcd705

• 19.8 Avg MPG

• Mercedes-Benz E350

  2007 Mercedes-Benz E350 GAS V6
  Added Apr 2009 • 69 Fuel-ups

  Property of McLeanKing

• 20.4 Avg MPG