Based on data from 19 vehicles, 1,455 fuel-ups and 491,167 miles of driving, the 2021 Lexus RX450h gets a combined Avg MPG of 28.49 with a 0.27 MPG margin of error.

Any Engine Type 3.5L V6 ELECTRIC/GAS (15) 3.5L V6 FULL HYBRID EV-GAS (FHEV) (4) Any Body Style Sport Utility (6) Any Submodel F Sport (4) Base (15)

Below you can see a distribution of the fuel-ups with 40 outliers (2.68%) removed.

Following shows the average MPG of each of the 19 vehicles in the system.

• My RX450h

  2021 Lexus RX450h 3.5L V6 ELECTRIC/GAS Automatic CVT
  Added Aug 2021 • 98 Fuel-ups

  Property of asislen

• 31.3 Avg MPG

• My RX450h

  2021 Lexus RX450h F Sport 3.5L V6 ELECTRIC/GAS Automatic CVT
  Added Sep 2022 • 68 Fuel-ups

  Property of jrojas1993

• 28.0 Avg MPG

• My RX450h

  2021 Lexus RX450h F Sport 3.5L V6 FULL HYBRID EV-GAS (FHEV) Automatic CVT
  Added Aug 2021 • 195 Fuel-ups

  Property of kbarnes09

• 18.0 Avg MPG

• My RX450h F Sport

  2021 Lexus RX450h F Sport 3.5L V6 ELECTRIC/GAS Automatic CVT
  Added Aug 2021 • 126 Fuel-ups

  Property of jconnpac

• 28.5 Avg MPG

• Lexus RX450h

  2021 Lexus RX450h 3.5L V6 ELECTRIC/GAS Automatic CVT
  Added Jul 2021 • 167 Fuel-ups

  Property of DaveDilley

• 30.5 Avg MPG

• My RX450h

  2021 Lexus RX450h 3.5L V6 ELECTRIC/GAS Automatic CVT
  Added Jul 2021 • 106 Fuel-ups

  Property of mkgonzalez10

• 26.5 Avg MPG

• Doc Rock's RX

  2021 Lexus RX450h 3.5L V6 FULL HYBRID EV-GAS (FHEV) Automatic CVT Sport Utility
  Added Apr 2021 • 87 Fuel-ups

  Property of DocRock

• 36.5 Avg MPG

• Lexus RX450h

  2021 Lexus RX450h 3.5L V6 FULL HYBRID EV-GAS (FHEV) Automatic CVT Sport Utility
  Added Jun 2024 • 19 Fuel-ups

  Property of DoctorPaul

• 30.6 Avg MPG

• RX450h

  2021 Lexus RX450h 3.5L V6 ELECTRIC/GAS Automatic CVT
  Added Aug 2021 • 101 Fuel-ups

  Property of sccobiedoo

• 31.9 Avg MPG

• My RX450h

  2021 Lexus RX450h 3.5L V6 ELECTRIC/GAS Automatic CVT
  Added Aug 2021 • 243 Fuel-ups

  Property of wcjdds

• 26.8 Avg MPG

• Lexus

  2021 Lexus RX450h F Sport 3.5L V6 ELECTRIC/GAS Automatic CVT Sport Utility
  Added Aug 2021 • 64 Fuel-ups

  Property of fzavit

• 24.7 Avg MPG

• My RX450h

  2021 Lexus RX450h 3.5L V6 ELECTRIC/GAS Automatic CVT
  Added Nov 2020 • 73 Fuel-ups

  Property of Jiang

• 34.4 Avg MPG

• Lexus R450h

  2021 Lexus RX450h 3.5L V6 FULL HYBRID EV-GAS (FHEV) Automatic CVT Sport Utility
  Added Dec 2020 • 6 Fuel-ups

  Property of adcri

• 30.5 Avg MPG

• My RX450h

  2021 Lexus RX450h 3.5L V6 ELECTRIC/GAS Automatic CVT
  Added Sep 2021 • 59 Fuel-ups

  Property of cfarthing

• 25.1 Avg MPG

• Lexy

  2021 Lexus RX450h 3.5L V6 ELECTRIC/GAS Automatic CVT Sport Utility
  Added Jan 2021 • 79 Fuel-ups

  Property of vamaka

• 33.5 Avg MPG

• My RX450h

  2021 Lexus RX450h 3.5L V6 ELECTRIC/GAS Automatic CVT
  Added Dec 2020 • 54 Fuel-ups

  Property of nkalamkarian

• 23.1 Avg MPG

• My RX450h

  2021 Lexus RX450h 3.5L V6 ELECTRIC/GAS Automatic CVT
  Added Nov 2020 • 52 Fuel-ups

  Property of marknsue89

• 25.9 Avg MPG

• Lexus RX450H

  2021 Lexus RX450h 3.5L V6 ELECTRIC/GAS Automatic CVT Sport Utility
  Added Dec 2021 • 17 Fuel-ups

  Property of allyjaync

• 26.8 Avg MPG

• My RX450h

  2021 Lexus RX450h 3.5L V6 ELECTRIC/GAS Automatic CVT
  Added Aug 2021 • 6 Fuel-ups

  Property of dykstal

• 30.5 Avg MPG