Based on data from 105 vehicles, 8,802 fuel-ups and 2,252,747 miles of driving, the 2010 Lexus RX350 gets a combined Avg MPG of 19.33 with a 0.07 MPG margin of error.

Any Engine Type 3.5L V6 GAS (93) GAS (1) V6 GAS (9) Any Body Style Sport Utility (33) Any Submodel Base (93) Other (12)

Below you can see a distribution of the fuel-ups with 586 outliers (6.24%) removed.

Following shows the average MPG of each of the 105 vehicles in the system.

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• Midnight the RX350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Dec 2024 • 3 Fuel-ups

  Property of rickras20

• 22.1 Avg MPG

• Alexus

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed Sport Utility
  Added Feb 2024 • 39 Fuel-ups

  Property of tjgruney

• 21.4 Avg MPG

• 2010 Lexus RX350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed Sport Utility
  Added Aug 2010 • 247 Fuel-ups

  Property of wkwan

• 21.0 Avg MPG

• 2010 Lexus RX350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Mar 2019 • 25 Fuel-ups

  Property of johnchunter

• 18.1 Avg MPG

• RX350 (2010)

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Sep 2016 • 535 Fuel-ups

  Property of glennl

• 18.0 Avg MPG

• Lexus RX 350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added May 2022 • 29 Fuel-ups

  Property of Micfuelly

• 16.4 Avg MPG

• Erin’s RX350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Dec 2018 • 83 Fuel-ups

  Property of rdorfer

• 20.2 Avg MPG

• Gray Lexus

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Apr 2017 • 20 Fuel-ups

  Property of Alphaeus

• 46.9 Avg MPG

• RX 350 2010

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Oct 2017 • 161 Fuel-ups

  Property of toolcrib

• 19.0 Avg MPG

• Lexus

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed Sport Utility
  Added Oct 2022 • 116 Fuel-ups

  Property of rotsi0t

• 21.4 Avg MPG

• White Stallion

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed Sport Utility
  Added Jul 2020 • 62 Fuel-ups

  Property of michaelahess

• 22.0 Avg MPG

• Wife's Rig

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed Sport Utility
  Added Dec 2021 • 47 Fuel-ups

  Property of dabblebabble

• 18.5 Avg MPG

• My RX350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Jan 2017 • 135 Fuel-ups

  Property of GG23

• 19.6 Avg MPG

• Lexus

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Feb 2018 • 270 Fuel-ups

  Property of Cashaw

• 26.6 Avg MPG

• Friend's car

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed Sport Utility
  Added Aug 2023 • 6 Fuel-ups

  Property of parnell

• 25.1 Avg MPG

• 2010 Lexus RX350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added May 2022 • 112 Fuel-ups

  Property of lake123

• 22.4 Avg MPG

• My RX350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Jul 2017 • 229 Fuel-ups

  Property of red98dawg

• 18.9 Avg MPG

• My RX350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Feb 2023 • 12 Fuel-ups

  Property of emergency911

• 17.0 Avg MPG

• My RX350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Feb 2018 • 4 Fuel-ups

  Property of jbzgm

• 21.3 Avg MPG

• RX 350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed Sport Utility
  Added Oct 2020 • 91 Fuel-ups

  Property of dcollin9

• 18.8 Avg MPG

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