Based on data from 118 vehicles, 13,671 fuel-ups and 3,410,496 miles of driving, the 2006 GMC Sierra 2500 HD gets a combined Avg MPG of 14.25 with a 0.05 MPG margin of error.

Any Engine Type 6.0L V8 GAS (22) 6.6L V8 DIESEL (87) 8.1L V8 GAS (1) V8 DIESEL (3) V8 GAS (3) Any Body Style Sport Utility (1) Extended Cab Pickup (5) Crew Cab Pickup (33) Any Submodel SL (6) WT (6) SLE (30) SLT (69) Other (7)

Below you can see a distribution of the fuel-ups with 472 outliers (3.34%) removed.

Following shows the average MPG of each of the 118 vehicles in the system.

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• Quiv

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed
  Added Sep 2017 • 275 Fuel-ups

  Property of JordanTr

• 16.1 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLT 6.0L V8 GAS Automatic 5 Speed
  Added Dec 2024 • 3 Fuel-ups

  Property of Lestat1243

• 14.9 Avg MPG

• 2006 Duramax

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Apr 2018 • 274 Fuel-ups

  Property of oskam6

• 14.0 Avg MPG

• DirtyMax

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added May 2019 • 115 Fuel-ups

  Property of polarisn1

• 15.3 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLE 8.1L V8 GAS Automatic 5 Speed
  Added Sep 2022 • 113 Fuel-ups

  Property of firedave654

• 10.2 Avg MPG

• GMC

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed
  Added Mar 2017 • 456 Fuel-ups

  Property of BlueyZassoff

• 14.1 Avg MPG

• 2006 GMC Sierra 2500HD

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Jun 2018 • 691 Fuel-ups

  Property of tkemo648

• 16.1 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLE 6.6L V8 DIESEL Automatic 6 Speed
  Added Apr 2023 • 72 Fuel-ups

  Property of joesauto24

• 13.9 Avg MPG

• Duramax

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Oct 2017 • 212 Fuel-ups

  Property of bsneed

• 15.3 Avg MPG

• 2006 Sierra 2500 HD

  2006 GMC Sierra 2500 HD SL 6.6L V8 DIESEL Automatic 6 Speed
  Added Sep 2021 • 201 Fuel-ups

  Property of dillyboy

• 15.9 Avg MPG

• Ryan's Truck

  2006 GMC Sierra 2500 HD SLE 6.0L V8 GAS Automatic 5 Speed
  Added Mar 2017 • 356 Fuel-ups

  Property of rfoster

• 10.8 Avg MPG

• GMC 2500

  2006 GMC Sierra 2500 HD SLT 6.0L V8 GAS Automatic 4 Speed Crew Cab Pickup
  Added Mar 2023 • 244 Fuel-ups

  Property of cogborn84

• 11.0 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed
  Added Aug 2017 • 423 Fuel-ups

  Property of PrestonL

• 14.5 Avg MPG

• Red Solo Truck

  2006 GMC Sierra 2500 HD Custom Submodel V8 DIESEL
  Added Jun 2012 • 194 Fuel-ups

  Property of helmet

• 15.8 Avg MPG

• Duramax 2500HD

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Aug 2022 • 414 Fuel-ups

  Property of awesomeamerican

• 16.2 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLT 6.0L V8 GAS Automatic 4 Speed
  Added May 2022 • 85 Fuel-ups

  Property of theminthawk

• 11.5 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SL 6.6L V8 DIESEL Automatic 6 Speed
  Added Aug 2023 • 91 Fuel-ups

  Property of Andrew03

• 14.1 Avg MPG

• VEH-016

  2006 GMC Sierra 2500 HD SLE 6.0L V8 GAS Automatic 4 Speed
  Added Jan 2023 • 113 Fuel-ups

  Property of bentleylandscape

• 9.5 Avg MPG

• Truck

  2006 GMC Sierra 2500 HD SL 6.6L V8 DIESEL Standard 6 Speed
  Added Mar 2018 • 192 Fuel-ups

  Property of Bacons2018

• 14.1 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed
  Added Nov 2022 • 107 Fuel-ups

  Property of sixsix_tom

• 15.4 Avg MPG

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