Interesting question.
On the FI systems I've seen, enrichment is by way of an increase in injector pulsewidth, so to minimize losses I guess you would want to have as fast of a warmup as possible, with as low of an engine speed (i.e. top gear). In other words, take the highway route and shove it into overdrive.
However I believe some FI systems will modify the target A/F ratio during warmup, which would make RPM irrelevant, and would only make the amount of time until warmup relevant. In this scenario the highway would still be better because you would warm up faster (higher engine load) and get into "normal" (closed loop, 14.7:1 AFR) mode sooner.
Of course I'm just blabbering with no hard statistics, so I'd be curious to see you do a few tankfuls of each method and see if you can see some meaningful results.
-Bob C.
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