even if you slow down to 70mph you'd notice huge savings.
acetone was kind of the "tickle me elmo" of fuel economy for a while. Everyone wanted to do it... everyone claimed it was awesome, and then everyone just put it in the trash after their kid didn't want it two weeks after christmas.
Inflate the tires properly, get a tune-up, and slow down. I like to stay at 65mph on road trips, but that isn't always viable.
oh, and SVOBoy is right. Radiators are built for the worst case scenario, much like prenuptial agreements. you don't really need them, but just in case... you get the idea. Most people have had luck by covering most of their radiator but leaving a little space for some air to get in.
Oh, and welcome to the site... pickin' ain't easy, eh?