What I have seen is the torque curve and or fuel curve will be the same on an engine dyno and chassis dyno. The leverage from the transmission adds torque multiplication so the torque read out is just higher.
I have, and several others have built fuel maps on chassis dyno's. On a inertia dyno you will have to do some fine tuning when your road testing but the fuel curve will stay the same. So all you do is +/- fuel across the board.
On a load type dyno you can simulate the weight of the car etc. But its a little more complicated then that.
1)I think the question is at lighter load does the torque curve drop to a better part of the island?
2)The other question is if you shift at a lower rpm before MBT will this save fuel based on the fact of only so much torque is needed to accelerate the vehicle to a certain speed?
Combine #1 and #2 together and you will have a much improved driving technique for saving fuel?