I had a puncture on my way to class last week. It was some kind of stainless steel self-drilling machine screw with this weird bonded rubber/stainless washer. Luckily I noticed it almost immediately and stopped within about a mile.
I could have pulled out the jack and spare, but I had a faster alternative... I carry a
plug kit and
pump around with me. I found the screw in the tire, rolled the car forward about a foot so it was in a convenient position to work on, pulled out the plug kit, a pair of pliers (to remove the screw) and the pump. After a little prep, I removed the screw, reamed out the hole and worked the plug in before the tire had drained. I hooked up the pump, cut off the excess plug, cleaned off the tools, packed up and was back on the road. Total time lost: about 15 mins.