I think going after a normal-looking/performing car, and not a commuter vehicle would be a better idea.
My idea is this:
1) The vehicle must be a midsize car capable of seating five 200 pound, 6'5" adults
2) Must be able to run on renewable energy
3) Must obtain at least 50 mpg
4) Must obtain 0-60 mph acceleration of under 8 seconds
5) Must not appear radically different from the cars of today
6) Must cost under $30,000
A midsize car with the above seating capacity is easy and outlined above. This would basically be a vehicle at least the size of a Toyota Prius. Trimming out much dead weight from the interior could yield such a car with a weight around 2,900 pounds. Due to the car's size, frontal area will be about 23 square feet.
0-60 mph of 8 seconds or less? Must run on renewables? This calls for a diesel with at least 200 horsepower. Take a turbodiesel from a VW Jetta, add a performance chip and additional turbo boost.
50 mpg? The frontal area is set in stone, so the drag coefficient must be worked on. A .18 Cd sounds pretty reasonable given past accomplishments in the auto industry in regards to their concept vehicles or in the case of small companies, actual production cars. Google search the GM Precept(.16 Cd), Dodge Intrepid ESX-2(.20 Cd), Ford Probe V(.137 Cd), Alfa Romeo BAT7(.19 Cd), Tatra T77a(.21 Cd), among others. Basically, a Cd of .18 and 23 square foot frontal area yields a Cd*A of 4.14, about half that of a normal car. But aerodynamics only affects fuel economy at higher speeds. We already set the weight in stone at 2,900 pounds. So to get this efficiency? We're going to need LRR tires, synthetic transmission oil, low friction wheel bearings, and brakes that don't drag.
Appearance? Something along the lines of those cars I told you to google search.
GM Precept:
Dodge Intrepid ESX-2:
Those look like something people will buy. They look rather normal, if not sporty.
Cost? Well, we haven't used exotic composite materials, or exotic engine components. We haven't used a hybrid drive. Aerodynamics add little, if any additional cost to the manufacturing price of the car because it's simply a matter of how the car is shaped. Realistically, this could be a $20,000-25,000 car.
So overall, could these goals be met?
1) Midsize car? yes.
2) Capability to use renewable energy? Yes. It's a diesel and can be fit to run on B100.
3) At least 50 mpg? Yes. Diesel midsize cars in Europe without significant efficiency modifications like Mercedes' V8 diesels are already doing over 25 mpg combined. This car would probably get around 60-70 mpg with the outlined efficiency modifications and a more efficient diesel powerplant.
4) 0-60 mph acceleration under 8 seconds? Probably. 200 HP in a 2,900 pound car would theoretically allow 0-60 in the low 7-second region. As an added bonus, with the low drag design, top speed would be roughly 170 mph with the right gearing.
5) Normal appearance? Certainly achievable.
6) Under $30,000? Yes. No hybrid drive and no exotic components would make this a car that is certainly cheaper to produce than today's hybrids. It could probably sell for about the same as most entry level midsize cars, around $20,000-25,000.