Today, I was driving on the highway from Regina to Saskatoon and got a lovely 70+ mpg @ 50mph when the crazy wind was tailing me

, but when I turned around heading back to the city, the same speed returned 34mpg

.
So then I wondered:
If I wanted to average 50mph on the highway both ways, what would be the best driving technique in strong winds? Doing 50mph both ways? or say 40mph with tail wind and 60mph with headwind? Or vice-versa? Or would it make any overall mpg difference at all?
I'd test it myself, but the wind is always changing on the prairies. My gut feeling is that if my car is going to get crappy FE in the wind, I may as well cruise at a higher speed at get to my destination. Whereas if there's a nice tail wind, I'll slow down a couple mph and reap the great FE.