Higher load is a good thing, as long as you're not wasting the energy produced. Search the forum and the internet for BSFC (Brake Specific Fuel Consumption), a measurement of an engine's fuel efficiency (not a vehicle, just an engine).
In practical application, this means that while you don't look to maximize your LOD statistic, you do want to make as much torque as you can use, at as low an RPM as agrees with your engine. Keep your RPM down and don't be afraid to be heavy on the accelerator. Set one of your ScanGauge's displays to Open/Closed Loop and avoid Open Loop, which you may get at WOT (Wide Open Throttle).
That was a major part of how I got great results from my 2008 VW. That car was also a very good match for that strategy, though; it had too much torque and ran smoothly right from idle RPM even at WOT. It also had a wideband O2 sensor that allowed it to stay in closed loop at WOT. The 2007 Sierra 4.3 probably doesn't have a wideband O2. However, to its advantage, I bet it has decent wide ratio gearing so you can keep RPM low at a variety of speeds...that VW had a gear for every speed, and that gear was 5th. I could drive that car only ever using 2nd and 5th and it would be like using all 5 gears in my Buick.
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