You might be able to keep experimenting upwards with the tire pressure. I recommend against exceeding the maximum pressure stamped on the side of the tires, which is probably 44 or 51psi. OTOH, you may have already found the highest pressure that works for you.
A lot of strategies commonly used are not applicable to highway driving. For example, avoiding the brakes; every time you brake you waste energy that you already spent gas making. So, you would take curves with as little braking as possible, and try to catch the "green wave" of synchronized traffic lights. You could learn your car's DFCO behavior and be sure to DFCO when slowing/stopping. There's no braking on the highway.
However, for mostly highway driving there's fewer techniques to apply. You're already driving slower and Engine Off Coasting (EOC) when possible. It might be possible to Pulse & Glide (P&G) or even EOC+P&G on the highway, especially since you're patient enough to go 50mph.
You could try drafting, if you can find a tractor-trailer going 50mph. There's a good thread about drafting linked in my sig, but here's cliff's notes:
- Find a clean full-length box trailer. Don't draft anything that might be a flatbed (even with sides attached), as rocks are likely to be falling from it.
- Keep a safe 2 to 3 second distance, which is a little further than a common tailgater gets from such trucks. If you get too close the turbulence destroys the draft.
With summer coming, you will probably find better fuel economy on the highway using air conditioning than open windows. You might also try other cooling techniques, like a cold wet cloth draped on your neck. There was a thread about that.
I know there's got to be a couple techniques I'm forgetting that apply to highway driving.
So without further techniques to apply, we get into modification territory:
- Warm Air Intake - user maximillian just made one for his late model Accent: http://www.gassavers.org/showthread.php?t=10825
- Radiator or grille blocking
- Extended air dam
- Tire deflectors
- Kammback or boattail
- Taller gears - 5th gear, final gear, or taller tires
- Removal of racks, antennas, other protruberances