I have an auto (Nissan) and have been using Mobil synth ATF and Lubegard trans additive.
Have driven this car for about 70K miles (has 158K on it) and early on it had a problem where it wouldn't shift right...failing to drop into 1st...but doing so with a clunk after stopping.
I fully flushed the ATF several Xs and added the Mobil ATF. This didn't solve the problem...but when I added the Lubegard additive...the "clunk" happened one more time and hasn't happened since.
Basic idea is that to prolong the life of an auto...the flushing process and then use of synth ATF will remove some varnish and clutch grit...and the Lubegard will further reduce the trans temps and help reduce friction.
http://www.lubegard.com/automotive/trans_atf.html
Need to be careful and use the right type for your trans though.
There is a difference between a machine type flush and doing it yourself thru the radiator cooling lines. The DIY method involves nothing more than exchanging in clean ATF...running it awhile and then flushing it again.
Eventually you put in the synth ATF.
Using a machine or a flushing fluid CAN cause problems.
Why do I use Mobil synth ATF and Lubegard? The Mobil is easy to find...but isn't cheap. The Lubegard ($12?) is endorsed by several OEMs...and can be found locally also (NAPA?)...but main thing is....it works.