Based on data from 18 vehicles, 596 fuel-ups and 184,175 miles of driving, the 2006 GMC Sierra 3500 gets a combined Avg MPG of 12.69 with a 0.33 MPG margin of error.

Any Engine Type 6.0L V8 GAS (2) 6.6L V8 DIESEL (10) V8 DIESEL (5) Any Body Style Extended Cab Pickup (2) Crew Cab Pickup (6) Any Submodel WT (2) SLT (4) SLE (7) Other (5)

Below you can see a distribution of the fuel-ups with 46 outliers (7.17%) removed.

Following shows the average MPG of each of the 18 vehicles in the system.

• My Sierra 3500

  2006 GMC Sierra 3500 WT 6.0L V8 GAS Automatic 4 Speed
  Added May 2021 • 6 Fuel-ups

  Property of G650

• 7.5 Avg MPG

• New Jesse

  2006 GMC Sierra 3500 SLT 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Nov 2023 • 27 Fuel-ups

  Property of CJGuy

• 15.6 Avg MPG

• BFT

  2006 GMC Sierra 3500 SLE 6.6L V8 DIESEL Automatic 6 Speed
  Added Sep 2016 • 53 Fuel-ups

  Property of Palmy1

• 12.8 Avg MPG

• 2006 GMC 6.0

  2006 GMC Sierra 3500 SLE 6.0L V8 GAS Automatic 4 Speed Extended Cab Pickup
  Added Jul 2024 • 5 Fuel-ups

  Property of z49racing

• 12.5 Avg MPG

• Old Duramax

  2006 GMC Sierra 3500 WT
  Added Jul 2024 • 177 Fuel-ups

  Property of Eben85

• 18.9 Avg MPG

• Diesel

  2006 GMC Sierra 3500 SLE 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Oct 2017 • 13 Fuel-ups

  Property of RandyJY

• 26.7 Avg MPG

• My Sierra 3500

  2006 GMC Sierra 3500 SLT 6.6L V8 DIESEL Automatic 6 Speed
  Added Aug 2022 • 3 Fuel-ups

  Property of Kamo_5

• 18.2 Avg MPG

• 3500 GMC

  2006 GMC Sierra 3500 SLE 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Sep 2018 • 118 Fuel-ups

  Property of drmike9327

• 12.9 Avg MPG

• GMC - Sierra 3500

  2006 GMC Sierra 3500 SLE 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Aug 2017 • 99 Fuel-ups

  Property of pblocal

• 11.8 Avg MPG

• Big Blue

  2006 GMC Sierra 3500 SLT 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Jun 2015 • 56 Fuel-ups

  Property of rpar86

• 13.8 Avg MPG

• My Sierra 3500

  2006 GMC Sierra 3500 SLE 6.6L V8 DIESEL Automatic 6 Speed Extended Cab Pickup
  Added Apr 2018 • 46 Fuel-ups

  Property of southwick

• 13.4 Avg MPG

• Dually

  2006 GMC Sierra 3500 SLE 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Sep 2017 • 29 Fuel-ups

  Property of Centex

• 13.2 Avg MPG

• 2006 Dually Duramax

  2006 GMC Sierra 3500 SLT 6.6L V8 DIESEL Automatic 6 Speed
  Added Aug 2016 • 56 Fuel-ups

  Property of ArtieBar64

• 8.6 Avg MPG

• BigBluLbz

  2006 GMC Sierra 3500 DIESEL V8
  Added Nov 2011 • 25 Fuel-ups

  Property of jonroy

• 17.5 Avg MPG

• dually

  2006 GMC Sierra 3500 DIESEL V8
  Added Feb 2014 • 7 Fuel-ups

  Property of guyluky

• 11.1 Avg MPG

• 2006 GMC

  2006 GMC Sierra 3500 DIESEL V8
  Added May 2012 • 7 Fuel-ups

  Property of nuutron

• 14.1 Avg MPG

• Duramax

  2006 GMC Sierra 3500 DIESEL V8
  Added Mar 2012 • 44 Fuel-ups

  Property of Cheeks

• 14.7 Avg MPG

• Dually

  2006 GMC Sierra 3500 DIESEL V8
  Added May 2010 • 13 Fuel-ups

  Property of LReinders

• 13.3 Avg MPG