Based on data from 117 vehicles, 13,560 fuel-ups and 3,382,715 miles of driving, the 2006 GMC Sierra 2500 HD gets a combined Avg MPG of 14.25 with a 0.05 MPG margin of error.

Any Engine Type 6.0L V8 GAS (21) 6.6L V8 DIESEL (87) 8.1L V8 GAS (1) V8 DIESEL (3) V8 GAS (3) Any Body Style Sport Utility (1) Extended Cab Pickup (5) Crew Cab Pickup (33) Any Submodel SL (6) WT (6) SLE (30) SLT (68) Other (7)

Below you can see a distribution of the fuel-ups with 471 outliers (3.36%) removed.

Following shows the average MPG of each of the 117 vehicles in the system.

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• Decal Truck

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed
  Added Jun 2018 • 10 Fuel-ups

  Property of Decalman

• 13.9 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed
  Added Mar 2017 • 81 Fuel-ups

  Property of DewmanCO

• 14.5 Avg MPG

• Truck

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Jun 2018 • 32 Fuel-ups

  Property of ssm04

• 14.3 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLE 6.0L V8 GAS Automatic 6 Speed
  Added Nov 2018 • 11 Fuel-ups

  Property of brcase

• 12.2 Avg MPG

• Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed
  Added Jun 2018 • 23 Fuel-ups

  Property of jvetterl

• 16.2 Avg MPG

• Work Truck

  2006 GMC Sierra 2500 HD WT 6.0L V8 GAS
  Added Jan 2019 • 49 Fuel-ups

  Property of Ullr

• 9.7 Avg MPG

• GMC Sierra

  2006 GMC Sierra 2500 HD SLE 6.6L V8 DIESEL Automatic 5 Speed Crew Cab Pickup
  Added Feb 2010 • 118 Fuel-ups

  Property of Mediator

• 24.1 Avg MPG

• Truck

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed
  Added Aug 2016 • 124 Fuel-ups

  Property of suasman

• 15.6 Avg MPG

• Big Blue

  2006 GMC Sierra 2500 HD SL 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Feb 2017 • 40 Fuel-ups

  Property of Blue06Sierra

• 14.6 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD WT 6.0L V8 GAS Automatic 5 Speed
  Added Jul 2017 • 6 Fuel-ups

  Property of shanebo

• 9.8 Avg MPG

• 2500HD

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 5 Speed
  Added Sep 2016 • 760 Fuel-ups

  Property of tstanley2128

• 17.3 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLT 6.0L V8 GAS Automatic 6 Speed
  Added Jan 2017 • 5 Fuel-ups

  Property of deadpoo

• 10.5 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed
  Added Jun 2017 • 3 Fuel-ups

  Property of DanJones

• 16.7 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLE 6.6L V8 DIESEL Automatic 6 Speed
  Added Jun 2017 • 3 Fuel-ups

  Property of smirnoff

• 13.3 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 5 Cab & Chassis (4 Door)
  Added Aug 2015 • 179 Fuel-ups

  Property of PrestonL

• 16.1 Avg MPG

• 1BuiltDMAX

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Nov 2013 • 30 Fuel-ups

  Property of AddMoreBoost

• 14.2 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed
  Added Dec 2016 • 7 Fuel-ups

  Property of jonnyxkash

• 13.8 Avg MPG

• GMC Sierra

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 5 Speed Crew Cab Pickup
  Added Aug 2015 • 10 Fuel-ups

  Property of angelacatz

• 16.1 Avg MPG

• The truck

  2006 GMC Sierra 2500 HD SLE 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Nov 2013 • 66 Fuel-ups

  Property of diggetydawg

• 14.3 Avg MPG

• Sierra

  2006 GMC Sierra 2500 HD WT 6.6L V8 DIESEL Automatic 6 Speed
  Added Sep 2016 • 91 Fuel-ups

  Property of chriscline

• 18.2 Avg MPG

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