Based on data from 118 vehicles, 13,809 fuel-ups and 3,444,942 miles of driving, the 2006 GMC Sierra 2500 HD gets a combined Avg MPG of 14.24 with a 0.05 MPG margin of error.

Any Engine Type 6.0L V8 GAS (22) 6.6L V8 DIESEL (87) 8.1L V8 GAS (1) V8 DIESEL (3) V8 GAS (3) Any Body Style Sport Utility (1) Extended Cab Pickup (5) Crew Cab Pickup (33) Any Submodel SL (6) WT (6) SLE (30) SLT (69) Other (7)

Below you can see a distribution of the fuel-ups with 476 outliers (3.33%) removed.

Following shows the average MPG of each of the 118 vehicles in the system.

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• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed
  Added Nov 2022 • 116 Fuel-ups

  Property of sixsix_tom

• 15.5 Avg MPG

• DirtyMax

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added May 2019 • 117 Fuel-ups

  Property of polarisn1

• 15.3 Avg MPG

• Tritnee

  2006 GMC Sierra 2500 HD SLE 6.6L V8 DIESEL Automatic 6 Speed
  Added Jul 2024 • 30 Fuel-ups

  Property of Lord_Commander

• 15.6 Avg MPG

• 2006 Sierra 2500 HD

  2006 GMC Sierra 2500 HD SL 6.6L V8 DIESEL Automatic 6 Speed
  Added Sep 2021 • 206 Fuel-ups

  Property of dillyboy

• 15.9 Avg MPG

• VEH-016

  2006 GMC Sierra 2500 HD SLE 6.0L V8 GAS Automatic 4 Speed
  Added Jan 2023 • 120 Fuel-ups

  Property of bentleylandscape

• 9.5 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLE 6.6L V8 DIESEL Automatic 6 Speed
  Added Feb 2017 • 363 Fuel-ups

  Property of HomerDMAX

• 16.4 Avg MPG

• GMC

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed
  Added Mar 2017 • 462 Fuel-ups

  Property of BlueyZassoff

• 14.1 Avg MPG

• Quiv

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed
  Added Sep 2017 • 277 Fuel-ups

  Property of JordanTr

• 16.0 Avg MPG

• Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLT 6.0L V8 GAS Automatic 5 Speed
  Added Dec 2024 • 9 Fuel-ups

  Property of Lestat1243

• 13.6 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SL 6.6L V8 DIESEL Automatic 6 Speed
  Added Aug 2023 • 96 Fuel-ups

  Property of Andrew03

• 13.9 Avg MPG

• 04 Yukon XL LBZ

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed Sport Utility
  Added Mar 2018 • 298 Fuel-ups

  Property of jamisondonato

• 15.1 Avg MPG

• Duramax 2500HD

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Aug 2022 • 419 Fuel-ups

  Property of awesomeamerican

• 16.3 Avg MPG

• 2006 GMC Sierra 2500HD

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Jun 2018 • 700 Fuel-ups

  Property of tkemo648

• 16.1 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLT 6.0L V8 GAS Automatic 4 Speed
  Added May 2022 • 91 Fuel-ups

  Property of theminthawk

• 11.5 Avg MPG

• Red Solo Truck

  2006 GMC Sierra 2500 HD Custom Submodel V8 DIESEL
  Added Jun 2012 • 197 Fuel-ups

  Property of helmet

• 15.7 Avg MPG

• Truck

  2006 GMC Sierra 2500 HD SL 6.6L V8 DIESEL Standard 6 Speed
  Added Mar 2018 • 198 Fuel-ups

  Property of Bacons2018

• 14.0 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLE 8.1L V8 GAS Automatic 5 Speed
  Added Sep 2022 • 119 Fuel-ups

  Property of firedave654

• 10.2 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLE 6.6L V8 DIESEL Automatic 6 Speed
  Added Apr 2023 • 75 Fuel-ups

  Property of joesauto24

• 13.8 Avg MPG

• 2006 GMC Sierra 2500 SLE

  2006 GMC Sierra 2500 HD SLE 6.6L V8 DIESEL Automatic 6 Speed
  Added Sep 2016 • 456 Fuel-ups

  Property of 911never4get

• 12.5 Avg MPG

• Big Red

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Apr 2024 • 15 Fuel-ups

  Property of masseyk

• 10.8 Avg MPG

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